Ann & Robert H. Lurie Children's Hospital of Chicago provides superior pediatric care in a setting that offers the latest benefits and innovations in medical technology, research and family-friendly design. As the largest pediatric provider in the region with a 140-year legacy of excellence, kids and their families are at the center of all we do. Ann & Robert H. Lurie Children's Hospital of Chicago is ranked in all 10 specialties by the U.S. News & World Report.

Seeking a highly motivated postdoctoral fellow to join Dr. Loretta Li's laboratory at Lurie Children's Hospital / Northwestern University. We are a recently established translational leukemia research laboratory that uses a variety of biochemical, molecular, and cell biology approaches to identify new therapeutic targets, develop preclinical models of disease, and test novel therapeutics both in vitro and in vivo using mouse models. Much of the lab's work to date has focused on Philadelphia chromosome (Ph) like B-cell acute lymphoblastic leukemia though the postdoc would have the opportunity to work on a new project focused on T-cell acute lymphoblastic leukemia. The successful candidate will be a team player capable of handling multiple tasks and adaptable to a fast-paced research environment.

Essential Job Functions:

The postdoctoral fellow will carry out an independent research project under the supervision of the principal investigator, Dr. Loretta Li. The successful candidate will be responsible for the following:

• Designing and conducting laboratory experiments to advance the research progress in the lab.

• Skilled handling of mice as needed to meet project goals.

• Analyzing data and troubleshooting experiments as needed.

• Maintaining detailed records of their laboratory work, results, and data analyses.

• Preparing presentations for lab meetings, journal clubs, research seminars, and research conferences.

• Synthesizing data and generating figures for grants, manuscripts, and presentations at the local, national, and international level.

• Working with the principal investigator to write grant proposals and progress reports related to the research project.

• Supervision and training of students and technicians in the lab.

• Sharing in the responsibilities of routine laboratory maintenance.

Knowledge, Skills and Abilities:

• Successful completion of a PhD at an accredited university in Molecular Biology, Cancer Biology, Biochemistry, Chemistry, or a related field is required. Candidates with an MD and at least 3 years of previous research experience will also be considered.

• Familiarity with basic handling of DNA, RNA, and protein, experience with molecular cloning, CRISPR/Cas9 genome editing, chromatin immunoprecipitation, and retroviral / lentiviral work. Experience with programing and bioinformatics analyses of large genomic datasets would be an asset.

• Comfort with handling mice is required. This includes previous experience with or willingness to learn about the breeding and weaning of animals, bleeding the mice, tail vein injections, IV, IP, and PO dosing, and necropsy.

• At least 1 first-author publication is required.

• 3 strong reference letters.

• Attention to detail in completing tasks and a strong work ethic is essential. This includes a willingness to critically read and keep up to date on the latest scientific literature, logically troubleshoot problems, and offer both intellectual and technical input during collaborative meetings.

• The candidate should have flexibility in their schedule to work on weekends and some evenings as needed to meet project goals.

• Working knowledge of computers, ability to work independently, and function as a team member is essential. Therefore, experience in regular interaction with outside groups is highly desirable.

• Excellent command of the English language and the ability to communicate effectively. This includes the ability to synthesize research findings for presentation in both oral and written formats.

• Strong organizational skills and a "can do" attitude. This includes the ability to establish priorities, react promptly to a large variety of requests, and the ability to keep the workplace clean and organized.

Education

Benefit Statement

For full time and part time employees who work 20 or more hours per week we offer a generous benefits package that includes:

Medical, dental and vision insurance

Employer paid group term life and disability

Employer contribution toward Health Savings Account

Flexible Spending Accounts

Paid Time Off (PTO), Paid Holidays and Paid Parental Leave

403(b) with a 5% employer match

Various voluntary benefits:

• Supplemental Life, AD&D and Disability

• Critical Illness, Accident and Hospital Indemnity coverage

• Tuition assistance

• Student loan servicing and support

• Adoption benefits

• Backup Childcare and Eldercare

• Employee Assistance Program, and other specialized behavioral health services and resources for employees and family members

• Discount on services at Lurie Children's facilities

• Discount purchasing program

There's a Place for You with Us

At Lurie Children's we embrace and celebrate diversity and equity in a serious way. We are committed to building a team with a variety of backgrounds, skills, and viewpoints - recognizing that diverse identities strengthen our workplace and the care we can provide to the Chicago community and beyond. We treat everyone fairly, appreciate differences, and make meaningful connections that foster belonging and allyship. This is a place where you can be your best, so we can give our best to the patients and families who trust us with their care.

Lurie Children's and its affiliatesare equal employment opportunity employers. We value diversity and are committed to creating an inclusive environment for all employees. All qualified applicants will receive consideration for employment without regard to race, color, sex, sexual orientation, gender identity or expression, religion, national origin, ancestry, age, disability, marital status, pregnancy, protected veteran status, order of protection status, protected genetic information, or any other characteristic protected by law.

Support email: